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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F5
All Species:
5.76
Human Site:
T269
Identified Species:
9.05
UniProt:
Q15329
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15329
NP_001077057.1
346
37610
T269
P
Q
K
S
S
M
A
T
Q
N
L
P
E
Q
H
Chimpanzee
Pan troglodytes
XP_511025
426
45548
Q254
L
P
K
P
A
L
A
Q
S
Q
E
A
S
R
P
Rhesus Macaque
Macaca mulatta
XP_001094919
346
37697
T269
P
Q
K
S
S
M
A
T
E
N
L
P
E
Q
H
Dog
Lupus familis
XP_853833
304
33793
L231
S
N
I
A
T
Q
N
L
P
E
H
V
S
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61502
335
36766
A259
P
Q
K
S
T
M
A
A
Q
N
L
P
E
Q
H
Rat
Rattus norvegicus
Q62814
300
33206
Q230
A
A
Q
N
L
P
E
Q
H
V
S
E
R
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517985
227
25092
A156
T
P
N
A
A
P
S
A
P
E
H
N
L
S
R
Chicken
Gallus gallus
Q90977
403
43534
T328
P
E
A
L
L
P
G
T
A
L
P
T
K
C
P
Frog
Xenopus laevis
NP_001086706
375
40890
N231
R
P
A
L
T
P
Q
N
D
I
A
T
S
P
A
Zebra Danio
Brachydanio rerio
NP_998597
393
42365
P231
A
A
A
A
P
T
K
P
T
A
N
S
T
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
P587
T
E
S
S
P
P
T
P
T
K
R
R
R
E
A
Honey Bee
Apis mellifera
XP_624285
300
34327
E230
V
I
S
D
E
D
E
E
D
D
A
E
L
I
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799123
356
39484
K279
M
L
T
E
T
K
I
K
E
E
V
T
E
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130952
446
48668
G350
A
D
C
N
K
V
T
G
M
E
S
N
I
H
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565831
483
52579
V386
H
D
I
E
A
L
T
V
D
N
P
E
T
A
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.8
97.9
78.9
N.A.
88.1
82.6
N.A.
57.2
33
58.1
56.2
N.A.
20.6
41
N.A.
51.9
Protein Similarity:
100
62.2
98.5
82.6
N.A.
90.1
84.3
N.A.
60.6
49.6
68.8
66.1
N.A.
29.6
55.2
N.A.
65.1
P-Site Identity:
100
13.3
93.3
0
N.A.
86.6
0
N.A.
0
13.3
0
0
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
33.3
100
20
N.A.
93.3
13.3
N.A.
20
26.6
6.6
6.6
N.A.
20
6.6
N.A.
33.3
Percent
Protein Identity:
N.A.
31.3
N.A.
28.1
N.A.
N.A.
Protein Similarity:
N.A.
45
N.A.
41.2
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
14
20
20
20
0
27
14
7
7
14
7
0
7
14
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
14
0
7
0
7
0
0
20
7
0
0
0
0
0
% D
% Glu:
0
14
0
14
7
0
14
7
14
27
7
20
27
20
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
7
% G
% His:
7
0
0
0
0
0
0
0
7
0
14
0
0
7
20
% H
% Ile:
0
7
14
0
0
0
7
0
0
7
0
0
7
7
7
% I
% Lys:
0
0
27
0
7
7
7
7
0
7
0
0
7
0
0
% K
% Leu:
7
7
0
14
14
14
0
7
0
7
20
0
14
0
0
% L
% Met:
7
0
0
0
0
20
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
7
7
14
0
0
7
7
0
27
7
14
0
0
0
% N
% Pro:
27
20
0
7
14
34
0
14
14
0
14
20
0
14
14
% P
% Gln:
0
20
7
0
0
7
7
14
14
7
0
0
0
20
7
% Q
% Arg:
7
0
0
0
0
0
0
0
0
0
7
7
14
7
14
% R
% Ser:
7
0
14
27
14
0
7
0
7
0
14
7
20
14
14
% S
% Thr:
14
0
7
0
27
7
20
20
14
0
0
20
14
0
0
% T
% Val:
7
0
0
0
0
7
0
7
0
7
7
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _